Introduction and aims: Improving in quality of care, provided by the health services for individuals and populations, will increase the likelihood of desired health outcomes and care consistent with current recommended guidelines. Australian health system dedicated major funds for improving in quality of endoscopy in order to increase adenoma and other early neoplastic lesions of the colon. Subsequently, it will increase colon cancer survival rate and the patient’s outcome. Proper endoscopy unites designed to provide a high-quality endoscopy care. This can categorized as below: 1. Preprocedural care 2. Intraprocedural care 3. Post procedural care Preprocedural care: In this section, proper endoscopy ward design is fundamental. In this regard, scope processing room need to consider as a separate most important part of every standard endoscopy unit. Before the procedures indications and complications of each procedure need to be assessing by the clinician or clinicians and also discuss with the patient. Documenting patient information and informed consent, conducting a standardized risk assessment before the endoscopic intervention, considering the patients medications, especially anticoagulants before the procedures and conducting a team time out before the procedure are essential. Common issues during this period include: appropriate indication, informed consent, risk assessment, formulation of a sedation plan, management of prophylactic antibiotics and antithrombotic drugs, and timeliness of the procedure. Intraprocedural care: During the procedure close observation of the patients vital signs, correct selection of anesthetic drugs are inseparable part of anesthetist job. Using proper scope size and collateral instruments, recognition of all abnormalities with good documentation and avoiding, recognizing, and managing the complications are mandatory. Considering appropriate ergonomic condition is vital for preventing musculoskeletal problems in endoscopist in long term. In modern endoscopy units using CO2 instead of air for reducing post procedure abdominal pain and distension is recommended. However, there is no difference in cecal intubation time, total examination time or success rate also the cost of Co2 vs O2 use need to consider. Moreover, water pump assisted endoscopy is also recommended not only for cleaning of endoscopy field but also better intubation of especially sigmoid colon. Post procedure: Proper procedure report, smooth recovery, explanation and discharge, detailed recommendations and follow-up plans, early detection, and proper management of possible complications, and considering patients feedback for improving the system. A good endoscopy unit should have metric measurements feedback for endoscopist for improving their important abilities like Adenoma Detection Rate (ADR), cecal intubation rate, Boston bowel preparation scale and withdrawal time. Finally, Swiss cheese model could prevent (Check &re check by other team members) complications causes by inevitable human errors.