: eosinophilic esophagitis is an increasing disease in the world .Prevalence of this disease is not determine in Iran.

As a part of cross sectional study,from patients over 14 years old that undergo endoscopy for eny cause; 2-3 esophageal biopsies were taken from 0.5 cm above Z line and 2-3 biopsies from proximal or middle esophagus and abnormal areas..After pathologic evaluation any eosinophil infiltration <15 in HPF of the epithelium was defined as esophageal eosinophilia.If eosinophil infiltration was≥15 in HPF Eosinophilic esophagitis was defined

In total 591 participants include in this study that 268(45.36 %) individuals were male and 323(54/65 %) were female. The average age was 65.5 years old in total and 62.3 in eosinophilic esophagitis group and 52/98 in Esophageal eosinophilia group.Prevalence of eosinophilic esophagitis was 2.37(n=14) and esophageal eosinophilia was 23.35 (n=138) per 100 individual .Prevalence of Eosinophilic esophagitis was more in males (10 (1.69 %in males and 4(0.68 %in females that was not significant .

Frequency of Esophageal eosinophilia and eosinophilic esophagitis was 23.35% and2.37%in our study that was the same as others therefor eosinophilic esophagitis is not rare in and shoude be considered in differential diagnosis of patient with esophageal symptoms.The age of eosinophilic esophagitis in this study is greater than other countries.