A recent outbreak of the novel coronavirus (SARS-COV-2) has been posing significant threats to global health since December 2019. It originated from Wuhan, China and was declared a pandemic by the World Health Organization (WHO) on March 11th, 2020. SARS-COV-2 has caused clusters of severe respiratory diseases, leading to ICU admissions and respiratory failure. Extra-pulmonary manifestations have been reported such as diarrhea and elevated liver enzymes. Liver diseases have been reported in 60% of patients with SARS-CoV-1 and since its genome sequence is more than 80% similar with the novel SARS-CoV-2, we should pay more attention to the largest organ in our body. To the best of our knowledge, non-alcoholic fatty liver disease (NAFLD) has not been mentioned in association with this novel viral disease. Here, we present our experience on patients suspicious for COVID-19 pneumonia who visited our emergency department in one of the main referral hospitals affiliated with Tehran University of Medical Sciences, Tehran, Iran from February 20 to March 28, and underwent chest CT scan. From a total of 441 patients who underwent CT scan in our outpatient setting, 125 (28.3%) were highly suggestive for COVID-19 pneumonia. According to the density of liver on non-contrast CT scan for non-invasive diagnosis of steatosis , we noticed that moderate to severe fatty liver disease was significantly more prevalent in those with COVID-19 pneumonia (16.8% vs 2.2%, p<0.0001), when liver was assessed in the upper abdomen cuts of chest CT scans. Recently, Zhe Xu reported a 50-year-old man who had died of COVID-19, with post-mortem liver biopsies showing moderate microvesicular steatosis and mild lobular and portal activity. In a retrospective study performed by Medeiros AK on 316 patients (204 RT-PCR positive; 112 RT-PCR negative), regression analysis showed a 4.7-times odds of steatosis in the COVID-19 positive group as compared to controls (OR 4.698; 95% CI 2.12–10.41, P < 0.001) . Whether NAFLD predisposes patients to COVID-19 or having common receptors and pathways causes their co-occurrence needs to be meticulously evaluated.