Dyspepsia is relatively a high chief complaint among patients in Iran, reducing the quality of life in the community and imposing tremendous economic pressure on the health care system. Knowing the underlying cause of dyspepsia is very important in treating patients. The present study aimed to evaluate the endoscopic findings of patients with dyspepsia in Ghaem Hospital, Mashhad, Iran

In this cross-sectional study, endoscopic findings in patients with dyspepsia, including epigastric pain or heartburn, postprandial fullness, and early satiety, were collected from Ghaem hospital from 2019 to 2020. The study results fall into two general categories; Functional or Organic dyspepsia.

Totally, 743 patients were studied, and 42.3% (n= 314) were male. The mean age was 46 years. Among participants, 85.6% (n= 636) of all patients were included in the functional dyspepsia group, and the rest were included in the Organic dyspepsia group. In the organic dyspepsia group, the highest frequency was related to peptic ulcer disease with 7.2% (n= 53). Moreover, the most common complaint was epigastric pain and heartburn. No significant association was found between comorbidities (P = 0.083), smoking, and gender (P = 0.532) with the risk of organic dyspepsia.

Dyspepsia is not necessarily accompanied by other comorbidities. The most mentioned chief complaint was epigastric pain or heartburn. Functional dyspepsia was the most common diagnosis in patients with dyspepsia, and the peptic ulcer was the leading cause of organic dyspepsia. There was no difference in the underlying cause of dyspepsia in genders.