Liver fibrosis is the main prognostic factor for chronic Hepatitis B. Convey of inactive hepatitis B to active one is usually done silently. In this setting accurate estimation of fibrosis is an important step in management of these patients. The aim of present study is to determine the impact of Fibroscan to evaluation of liver fibrosis in inactive chronic hepatitis B.

In a prospective study between Fev2016 - Jun2018, we evaluated the liver fibrosis among patients with inactive CHB by Fibroscan assessment. The inclusion criteria include presence of serum HBsAg more than 6 months, persistence normal liver enzymes during last six months, HBV – DNA viral load <20000 IU/ml.All other liver diseases were excluded. All patients underwent liver fibroscan .The factors influence on Fibroscan results such as sever obesity, cardiac and renal failure, decompensate cirrhosis and ascitis were excluded. The patients visited every six months. The eligible patients followed for one year.

210 patients have been enrolled in this study. The mean age was 37.49±12.8 years old and of them132 patients were male. Regarding the HBV DNA load ,48(22.9%),84(40%) and 78(37.1%) patient have viral load undetectable, under and more than 2000IU/ml respectively .The mean TE value among these patients was 5.8 ±1.26 kp. TE value more than 7.2kp was seen in 25(11.9%) patients with mean of 8.1±1.4 kp. There was no significant association between TE results and viral load levels in general . .Moreover , we did not observed a significant association between age and viral load and TE

We illustrated that inactive hepatitis B is not a innocent and benign condition and need regular follow up by liver enzyme, Vial load and TE evaluations