Several factors may contribute as a trigger to exacerbate the condition of patients with inflammatory bowel disease (IBD).

In this retrospective cross-sectional study, we assessed the document of 109 patients with the positive history of IBD exacerbation between March 2016 and March 2017. The parameters were recruited from the software. The mentioned parameters were assessed in terms of type and sevirity of disease by chi-square test using SPSS ver.20. Also, P ≤0.05 was considered as significant. Besids, binary logistic regression test was used to assess the associations between season of disease onset and IBD exacerbation, as odds ratios (OR) with confidence intervals (CI) 95%.

Among 109 patients with the positive history of IBD exacerbation, 96 patients (88.1%) had UC.The mean age of patients with IBD exacerbation was 38.14±14.66 years old. The disease duration in patients with UC and CD was 35.43 and 38.85 (mean of months), respectively. About 50% of these patients with infection, were strongyloides stercoralis positive. The occurrence of mild IBD exacerbation was significantly observed in spring in comparison to the other seasons (OR, 3.58; 95% CI, 0.1–1.04). Most of the UC patients were just prescribed salicylates (53.12%). Most of the CD patients with mild and severe activity were not smoker (p=0.058). It was marginally significant.

The evidences of distribution of strongyloides stercoralis infections among IBD patients with the history of exacerbation, considering this issue along with other environmental factors such as enhancing the nutritional quality and surface water is suggested to be studied in the future.