In this comparative case-control study the serum zinc and copper and selenium and vitamin D in fatty liver patients and control group was compared. Background: Non-alcoholic fatty liver disease is a common metabolic disease. Determination of contributing factors is important for better treatment and prognosis in the patients. Vitamins and minerals are important indices.

: In this case-control study 75 patients with non-alcoholic fatty liver disease and 50 control subjects were enrolled. The serum zinc and copper and selenium and vitamin D were measured by spectrophotometer method in single lab by same kit for each one of the indices and compared across the groups.

The results in this study demonstrated that serum zinc and selenium and vitamin D were same across the case and control groups (P>0.05) and serum copper level was higher in case group (P=0.001).

This study showed no significant difference between serum zinc and selenium and vitamin D in patients with non-alcoholic fatty liver disease versus control subjects; but the copper was higher in case group.