Celiac disease (CD), or as it is called Gluten enteropathy, could result in various complications such as liver abnormalities. Non-alcoholic fatty liver disease (NAFLD) affected 25.2% of individuals worldwide and has become one of the most common causes of cirrhosis. This study aimed to report the frequency of NAFLD, patients with CD in Golestan province, Northeast of Iran.

In this cross-sectional study, patients diagnosed with celiac disease based on a positive anti-tTG Ab and proved in small bowel biopsy were recruited between March 2018 and March 2020 (N=80), through the registry system located in Golestan Research Center of Gastroenterology and Hepatology, Northeast of IRAN. Ultrasonography was performed and NAFLD diagnosis was done based on attenuation of the liver itself (less than 40 Hounsfield Unit (HU)) or in comparison with the spleen (liver attenuation≤10, then spleen).

Among 80 CD patients (46 female, mean 39.13±12.5 years) NAFLD was reported in 34(43.5%), which was mild in 31(39%), moderate in 2 (2.5%) and severe in 1 (1.3%). One Cirrhosis and no hepatomegaly had been found.

In the present study NAFLD was seen in 43.5% of our CD patients that composed a large amount. This may be suggested to do closer follow-up of the complications in celiac disease.