Articles

Abdominal obesity as a significant risk factor for liver fibrosis in patients with elevated liver function test

8/12/2018 8:57:59 PM
Introduction

Sever obesity and elevated liver function test have been implicated in the development of nonalcoholic fatty liver disease (NAFLD). We evaluated the diagnostic value of liver stiffness measurement (LSM), by transient elastography (fibroscan); in patients referred to gastroenterology clinic in Gorgan, Northeast of Iran; with suspected NAFLD.

Method

In this cross-sectional study, one hundred patients underwent fibroscan and CAP measurement. Their Body Mass Index (BMI),Waist to Hip ratio (WHR) and blood pressure (SBP/DBP) have been measured.

Results

Among the study population 74.1% were men and 25.9% women,54.5% had Fibrosis grade ≥F2, 75% had steatosis grade=S3, 40% had Triglyceride (TG) higher than 150 mg/dl and 77% had abdominal obesity. Obesity and overweight have been reported in 98.5% of the studied population.

Conclusion

It seems that in our region, abdominal obesity is an important risk factor in NAFLD and out weight other factors such as hypertension, type 2 diabetes mellitus and hypertriglyceridemia.