Esophageal cancer is one of the most common and deadly cancers around the world. Despite the high prevalence of esophageal cancer in East Azarbaijan, many studies have not been conducted on the survival rate and its effective factors. The purpose of this study was to evaluate the effect of infection with Helicobacter pylori on the survival rate of patients with esophageal cancer.

This retrospective study was conducted in North-West of Iran 2006 - 2011, included of 532 patients with esophageal cancer that referred to Imam Reza (AS) Hospital in Tabriz. Of the 532 patients, 38 patients were investigated for Helicobacter pylori infection. Health status of patients followed by Telephone contact. Survival rate and the impact of Helicobacter pylori in survival rate was analyzed with Kaplan- Meier, Life Table in SPSS 16 software .

From 38 patient, 15 were women (39/48%), and 23 were men (60/53%).Median survival of patients with esophageal cancer associated with Helicobacter pylori infection was 18/60±3/37 (CI95%: 25/20-11/99) months, and the Median survival of patients with esophageal cancer without Helicobacter pylori infection was 11/40± 3/16 (CI95%: 17/60-5/19). P Value = 0/14.

The results of this study indicate that Helicobacter pylori infection increasing survival rates of esophageal cancer in our patients, but this is not statistically significant