Articles

Evaluation of the relative frequency of positive fit test with colorectal cancer in patients referred to comprehensive health service centers in Mashhad in 2018-2019

9/21/2021 9:44:51 PM
Introduction

One of the most common types of cancer in the world is colorectal cancer, it is the third most common cancer in both men and women. In this study, we investigated status of People regarding colorectal cancer using FIT test

Method

The present cross-sectional study carried out on the health assessment data of the population registered in the SINA system in 2018-2019, who entered the national program for the prevention and early detection of colorectal cancer during 2018 in the Mashhad. The demographic characteristics of the patients were recorded including FIT test results. Data were analyzed. A p-value less than 0.05 was considered statistically significant.

Results

A total of 140463 eligible individuals were screened for colorectal cancer using the FIT test, of which 8258 were positive (5.88%). Out of 7604 people (92%) who underwent colonoscopy and from those who underwent colonoscopy and in 145 people (1.9%) people were diagnosed with colon cancer. These results indicated a positive effect of age, nationality (non-Iranians), on the fit test result, while having a hard job and physical activity, Reduce the chances of a positive test result. In addition, the results showed bleeding from the anus during the last month , constipation during the last month , abdominal pain and feeling of full anus after defecation in the last month , weight loss of more than 10% in the last month , individual history of colorectal cancer , history of inflammatory bowel disease , family history of colorectal cancer in First-degree relative , history of colorectal cancer in second-degree relative under 50 years of age , history of inherited diseases increase the chances of a positive fit test.

Conclusion

This study showed that a high percentage of high-risk individuals in Mashhad in 2018 -2019 were positive for FIT test and a remarkable number of them were diagnosed with CRC after colonoscopy. Considering that doing screening is the first step in early detection of colorectal cancer are highly recommended.