Colorectal cancer (CRC) is the third most common cancer worldwide, and the incidence of CRC seems to increase gradually be increased gradually in some countries. The survival of CRC varies in different countries, is varied in different countries which attributed to the screening program and other risk factors. Generally, diagnostic approaches for CRC can be divided visual detection methods into visualize detection method and laboratory methods. Colonoscopy, sigmoidoscopy, and computed tomography colonography are considered as visual visualize methods and are widely used in cancer detection detection of cancer. Although visualize methods provide some benefits, some disadvantages such as late detection, are present , making them useless in rapidly progressing CRC patients. which make them useless in rapid progressive CRC patients. On the other hand, laboratory tests are developed to compensate for the disadvantages of visual methods. More recent progression in laboratory tests makes them able to superfine detection of CRC. For instance, molecular and genetic methods based on the components of cancer cells, like nucleic acid and proteins, can prognosticate further cancer development of cancer in susceptible patients. Alongside new therapeutic approaches developed within decades, the number of CRC detection methods is increased, which aimsed to reduce the duration between cancer initiation and detection. This review sought to survey the CRC detection methods, including conventional and recently-developed methods, to provide better insight into CRC diagnosis screening.